Ethyl apovincamin-22-oate
Vinpocetine
CAS: 42971-09-5;80038-06-8
Molecular Formula: C22H26N2O2
Ethyl apovincamin-22-oate - Names and Identifiers
Ethyl apovincamin-22-oate - Physico-chemical Properties
| Molecular Formula | C22H26N2O2 |
| Molar Mass | 350.46 |
| Density | 1.1260 (rough estimate) |
| Melting Point | 147-153 °C dec. |
| Boling Point | 484.44°C (rough estimate) |
| Specific Rotation(α) | D20 +114° (c = 1 in pyridine) |
| Flash Point | 207.506°C |
| Solubility | Soluble in chloroform or 96% ethanol, almost insoluble in water. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White fine powder |
| Color | white |
| Maximum wavelength(λmax) | ['315nm(EtOH)(lit.)'] |
| Merck | 14,9991 |
| pKa | 7.87±0.60(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Stability | Photosensitive |
| Sensitive | Sensitive to light |
| Refractive Index | 1.6500 (estimate) |
| MDL | MFCD00211233 |
| Physical and Chemical Properties | White crystalline powder, odorless and tasteless. Soluble in chloroform or 96% ethanol, a few insoluble in water. Melting point 147-153 °c (decomposition). [Α] D20 +114 °(C = 1, pyridine). UV maximum absorption (96% ethanol):229,275,315nm (h28200, 12000,7100). Acute toxicity LD50 mice, rats (mg/kg):534,503 oral; 240,133.8 intraperitoneal injection; 58.7,42.6 intravenous injection. |
| Use | Cerebrovascular medication |
Ethyl apovincamin-22-oate - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | 36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | JW4792000 |
| HS Code | 29399990 |
| Toxicity | LD50 in mice, rats (mg/kg): 534, 503 orally; 240, 133.8 i.p.; 58.7, 42.6 i.v. (Pálosi, Szporny), also reported as 161.2 mg/kg i.p. in mice (Cholnoky, Dmk) |
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